Effect of mechanically expanded vs self-expanding transcatheter aortic valve replacement on mortality and major adverse clinical events in high-risk patients with aortic stenosis: The REPRISE III randomized clinical trial
JAMA Jan 07, 2018
Feldman TE, et al. - Researchers sought to analyze if a mechanically expanded valve (MEV) was noninferior to an approved self-expanding valve (SEV) in high-risk patients with aortic stenosis undergoing transcatheter aortic valve replacement (TAVR). It was noted that the use of the MEV compared with the SEV did not yield inferior outcomes for the primary safety end point or the primary effectiveness end point, among high-risk patients with aortic stenosis. Hence, MEV could serve as a beneficial addition for TAVR in high-risk patients.
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