Chen Y, Lyu J, Xia Y, et al. - This is the first study investigating the connection between maternal unhealthy behaviors like lack of sleep, physical inactivity, and prolonged use of electronic devices during pregnancy and the risk of childhood allergies in a sex-specific manner. Six thousand two hundred thirty-six mother-child pairs from Shanghai Children Allergy Study were recruited, The International Study of Asthma and Allergies in Childhood questionnaire was adopted to assess respiratory allergic diseases. Data reported that 14.6, 16.2, and 21.0% of children had asthma, wheeze, and allergic rhinitis, respectively. Maternal unhealthy behaviors with a dose-response pattern during pregnancy might increase the risk of childhood respiratory allergies. Males were more prone to the association. The detection of modifiable maternal risk behaviors lies in the focus on intervention in early life to cope with growing childhood allergies.