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Effect of lymphadenectomy on the prognosis for N0 gallbladder carcinoma patients: A study based on SEER database

Cancer Medicine Sep 17, 2021

Wu B, Shen Y, Chen X, et al. - N0 gallbladder carcinoma (GBC) patients exhibit a significant survival benefit in correlation with receiving a greater number of lymph nodes removal (LNR). Hence researchers support the necessity for an extended lymph node dissection strategy in N0 GBC patients.

  • From the database named SEER (Surveillance, Epidemiology, and End Results database), researchers identified 1,406 N0 GBC patients for inclusion.

  • LNR was not performed in the majority of N0 GBC patients undergoing cancer-directed surgery (64.5%).

  • LNR was identified as an independent favorable prognostic factor of N0 GBC in multivariate regression analysis.

  • Finally, a nomogram for precise prediction of the prognosis of N0 gallbladder cancer patients was developed.

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