Yu J, et al. - In this noninferiority, open-label, randomized clinical trial, researchers compared 3-year disease-free survival for patients with locally advanced gastric cancer after laparoscopic distal gastrectomy or open distal gastrectomy. From September 2012 to December 2014, a total of 1056 eligible patients with clinical stage T2, T3, or T4a gastric cancer without bulky nodes or distant metastases were recruited. Data reported that the 3-year disease-free survival rate was 76.5% in the laparoscopic distal gastrectomy group and 77.8% in the open distal gastrectomy group. Findings revealed that laparoscopic distal gastrectomy compared with open distal gastrectomy did not result in inferior disease-free survival at 3 years among patients with a preoperative clinical stage indicating locally advanced gastric cancer.