Effect of insulin resistance on BMD and fracture risk in older adults
Journal of Clinical Endocrinology and Metabolism Mar 06, 2019
Napoli N, et al. - In community-dwelling, older non-diabetic individuals (n=2,398), researchers studied the correlation between insulin resistance (HOMA-IR), bone mineral density (BMD), and incident non-spine fractures. Greater IR was found to be related to higher BMD. However, contrary to the relationship between type 2 diabetes and fracture risk—after adjustment for BMI and BMD—the investigators found no consistent evidence that greater IR was linked to increased risk of fracture.
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