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Effect of infarct site on the clinical endpoints of thrombolytic-treated ST-elevation myocardial infarction

The American Journal of Emergency Medicine Apr 17, 2019

Gifft K, et al. – Researchers compared clinical endpoints (ie, in-hospital all-cause mortality, length of hospital stay, cardiogenic shock, and mechanical complications) of thrombolytic-treated ST-elevation myocardial infarction (STEMI) based on coronary artery distribution in a study population extracted from the 2014 Nationwide Readmissions Data using the International Classification of Diseases, ninth edition, clinical modifications codes for STEMI, thrombolytic infusion, and complications of STEMI. Thrombolytic-treated STEMI was principally diagnosed in 1,231 patients. STEMIs occurred in the left anterior descending (LAD) artery distribution in 431 patients, the left circumflex (LCX) artery distribution in 124, and the right coronary artery (RCA) distribution in 676. Thrombolytic-treated STEMIs in the RCA distribution were correlated with lower mortality, fewer cardiogenic shock, and shorter length of stay when compared with the LAD and LCX distributions. No differences in mechanical complications were noted based on the coronary distribution.

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