Bryan AD, et al. - Researchers herein compared a theory-based sexual risk-reduction intervention that included alcohol- and cannabis-focused content with an intervention that included alcohol-related content only and an intervention that did not include substance use content, in terms of reductions in sexually transmitted infections (STIs). They found that for reducing STI incidence among justice-involved adolescents, an intervention delivered in a motivational enhancement therapy format that included theory-based sexual risk reduction combined with alcohol- and cannabis-focused elements was effective. This 1-session manualized intervention could be delivered in the context of short-term detention and was easily disseminated to juvenile justice agencies.