Bouisset F, Ribichini F, Bataille V, et al. - Researchers examined the impact of gender on clinical results of rotational atherectomy (RA) percutaneous coronary intervention (PCI), by utilizing the Euro4C registry, an international prospective multicentric registry of RA PCI. A total of 966 patients were selected between October 2016 and July 2018. Of those, females were 267 (27.6%) in total. The female group was found to have a higher in-hospital major adverse cardiac event rate, defined as cardiovascular mortality, myocardial infarction, stroke/transient ischemic attack, target lesion revascularization, and coronary artery bypass grafting surgery. At 1 year follow-up, the rate of major adverse cardiac events was estimated to be 18.4% vs 11.2% in the female group vs in the male group. Overall, findings showed that worse clinical outcomes after RA PCI, during hospitalization as well as at 1 year follow-up, were experienced by women vs men.