Bouisset F, Ribichini F, Bataille V, et al. - Researchers sought to determine the impact of gender on clinical results of rotational atherectomy (RA) percutaneous coronary intervention (PCI), utilizing the Euro4C registry, an international prospective multicentric registry of RA PCI. A total of 966 patients were included between October 2016 and July 2018. Of those, women were 267 (27.6%) in total. The female group was found to have higher in-hospital major adverse cardiac event (MACE) rate (defined as cardiovascular mortality, myocardial infarction, stroke/transient ischemic attack, target lesion revascularization and coronary artery bypass grafting surgery). At one year follow-up, MACE rate was estimated to be 18.4% and 11.2% in the female group and in the male group, respectively. Overall, findings showed that worse clinical results were observed after RA PCI, during hospitalization as well as at one year follow-up, in women compared with men.