Dash C, et al. - Researchers performed this study on black women enrolled in the Focused Intervention on Exercise to Reduce Cancer (FIERCE) trial to gauge the impacts of supervised and home-based exercise on changes in metabolic syndrome (MetS) by breast cancer risk (high vs low). In this study including postmenopausal, obese, metabolically unhealthy black women (45 to 65 years old), intent-to-treat analyses using generalized estimating equation models were carried out to determine the intervention impacts on MetS, stratified by breast cancer risk. Findings revealed that obese, metabolically unhealthy black women at elevated risk for cancer may benefit from short-term aerobic activity regimens via an improved metabolic profile, which led to reduced breast cancer risk in these subjects.