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Effect of dexamethasone on analgesic efficacy of transverse abdominis plane block in laparoscopic gynecological procedures: A prospective randomized clinical study

Journal of Anaesthesiology Clinical Pharmacology Jul 01, 2019

Vetriselvan P, et al. - In this prospective, randomized, parallel treatment, double-blinded study performed on patients (n=40) undergoing laparoscopic gynecological procedures under general anesthesia, researchers compared duration of analgesia in relation to use of dexamethasone as an adjuvant with local anesthetic in transverse abdominis plane block (TAP) vs when administered systemically by intravenous route along with block only. The time to administration of first rescue analgesia was the primary outcome. Findings revealed that quality of analgesia of TAP block with 0.25% levobupivacaine was comparatively influenced by dexamethasone given in either of the routes.
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