Li MH, et al. - In patients undergoing surgery for lung adenocarcinoma, the impacts of combined epidural anaesthesia on the number of tumor-infiltrating lymphocytes (TILs) were investigated. As a consequence of using epidural anaesthesia for patients undergoing surgery for lung adenocarcinoma under general anesthesia, increased CD8⁺ T cells infiltration but decreased FOXP3⁺ T cells accumulation in tumor tissues was observed. As observed, epidural anaesthesia may impact TILs in a manner that preserves immune function.