Li MH, et al. - Researchers intended to explore the effects of combined epidural anaesthesia on the number of tumor-infiltrating lymphocytes (TILs) in patients undergoing surgery for lung adenocarcinoma. Patients undergoing radical resection for primary lung cancer were randomized to receive either combined epidural-general anaesthesia (Epi-GA) or general anaesthesia (GA). The use of epidural anaesthesia increased CD8⁺ T cells infiltration but decreased FOXP3⁺ T cells accumulation in tumor tissues for patients undergoing surgery for lung adenocarcinoma under general anesthesia. It was found to be probable that epidural anaesthesia could influence TILs in a manner that preserved immune function.