Volis I, Saliba W, Jaffe R, et al. - This retrospective study is done with 10,297 patients, to determine the long-term prognostic implications of polyvascular disease in patients suffering from coronary artery disease (CAD), as well as to further examine lipid goal attainment and its association with patient results. The participants had undergone coronary revascularization, classified as experiencing CAD alone (83.1%) or with multisite artery disease (MSAD) (16.9%) including cerebrovascular disease (CBVD) and/or peripheral artery disease (PAD). In patients with CAD, a higher burden of co-morbidities as well as progressive rise in long-term major adverse cardiovascular events was reported in correlation with the presence of CBVD and/or PAD. Non-attainment of lipid goals, which were related to a significantly lower risk for adverse events, was noted in more than half of CAD patients with or without MSAD.