Yang Y, Lueken U, Richter J, et al. - Researchers investigated how cognitive-behavioral therapy (CBT) influences the behavioral as well as neural correlates of the panic-associated semantic network among patients with panic disorder. This study involved patients with panic disorder and healthy controls. Post-CBT, the patient group demonstrated significant clinical improvements along with a decrease in relatedness and negative valence rating and attenuation of neural activation in the anterior cingulate cortex for processing of panic-trigger/panic-symptom word pairs. Overall, in panic disorder, a biased semantic network was supported, which was normalized post-CBT. A likely mechanism for future curative interventions is afforded by attenuation of anterior cingulate cortex activation for the processing of panic-related connections.