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Effect of body temperature on cerebral autoregulation in acutely comatose neurocritically ill patients

Critical Care Medicine Jul 20, 2018

Adatia K, et al. - Researchers performed this retrospective analysis in comatose patients to evaluate the link between body temperature and cerebral autoregulation. They used prospectively collected data for 85 acutely comatose patients (Glasgow Coma Scale score of ≤ 8) admitted to the neurocritical care unit of Johns Hopkins Hospital between 2013 and 2017. Using mixed random effects models with random intercept and multivariable logistic regression analysis, they evaluated the link between hourly temperature and cerebral oximetry index, as well as between temperature and clinical outcomes. They observed an association of increasing body temperature with worsening cerebral autoregulation, as measured by cerebral oximetry index, in acute coma patients.

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