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Effect of apneic oxygenation on tracheal oxygen levels, tracheal pressure, and carbon dioxide accumulation: A randomized, controlled trial of buccal oxygen administration

Anesthesia & Analgesia May 23, 2019

Toner AJ, et al. - Whether maintenance of a tracheal oxygen concentration >90% during apnea can be consistently achieved with buccal oxygen administration and whether significant risks of hypercarbia or barotrauma exist were investigated in this study performed on healthy, nonobese patients (n = 20). Maintained high tracheal oxygen concentrations were reliably provided by buccal oxygen administration, but early arterial desaturation could still occur via mechanisms other than device failure. Although a similar risk of hypercarbia was noted in comparison to other approaches, the risk of barotrauma was negligible. Based on the findings, researchers concluded that it is feasible to continuously measure advanced physiological parameters in an apneic oxygenation trial and this can assist with device evaluation.
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