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Effect of anti-hypertensive medication history on arteriovenous fistula maturation outcomes

American Journal of Nephrology Aug 09, 2018

Wang K, et al. - How angiotensin converting enzyme inhibitor (ACE-I) and angiotensin receptor blockers (ARBs), calcium channel blockers (CCBs), beta-blockers, and diuretics impact the maturation of newly created arteriovenous fistulas (AVFs) was examined. From the Hemodialysis Fistula Maturation Study, a multi-center, prospective cohort study of AVF maturation, researchers evaluated 602 participants. Findings revealed no significant impact of ACE-I/ARB, beta-blocker, and diuretic use on AVF maturation outcomes. Changes in AVF diameter or blood flow over 6 weeks following surgery were not evident with any of the antihypertensive medication classes. Association of CCB use with a lower risk of overall AVF maturation failure was seen.

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