Schenker Y, Althouse AD, Rosenzweig M, et al. - Outcomes of this cluster randomized clinical trial of the CONNECT intervention vs standard care in patients with metastatic solid tumors indicated no improvement in patient-reported outcomes at 3 months in correlation with implementation of a primary palliative care intervention delivered by oncology nurses.

• A total of 672 patients with metastatic solid tumors were included in this trial.

• No improvement in quality of life was observed in correlation with implementing an oncology nurse–led primary palliative care intervention vs standard oncological care alone.

• Among patients with advanced cancer who lack access to palliative care specialists, most may benefit from implementing primary palliative care interventions with a higher dose intensity.