Papapostolou S, Dinh DT, Noaman S, et al. - Researchers used the Melbourne Interventional Group registry to assess the impact of age in an all-comers population receiving percutaneous coronary intervention (PCI). Data were analyzed for 29,012 consecutive patients receiving PCI. A comparison was performed between 25,730 patients < 80 year old (78% men, mean age 62 ± 10 years; non-elderly cohort) vs 3,282 patients ≥ 80 year old (61% men, mean age 84 ± 3 years; elderly cohort). The elderly cohort had higher in-hospital, 30-day as well as long-term all-cause mortality. Independent predictors of long-term all-cause mortality, in multivariate Cox regression analysis, were: estimated glomerular filtration rate < 30 mL/min/1.73 m², cardiogenic shock, ejection fraction < 30%; and age ≥ 80 years. Overall, the elderly cohort was identified as a high-risk population of patients with increasing age being related to poorer long-term mortality. Therefore, when individualising treatment in elderly patients, age should essentially be given consideration.