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Effect of adding midazolam to bupivacaine during rectus sheath block: A randomised controlled trial

Acta Anaesthesiologica Scandinavica May 23, 2018

Ammar A, et al. - Researchers determined the impact of adding midazolam to bupivacaine on rectus sheath (RS) block in patients undergoing umbilical or epigastric hernia repair, focusing on post-operative 48 h morphine consumption, analgesia duration, post-operative pain, post-operative nausea and or vomiting (PONV), somnolence or any adverse drug reactions. Two patient groups were formed: Group I received 20 ml of bupivacaine hydrochloride 0.25% + midazolam 50 μg/kg in 2 ml saline 0.9% (Midazolam group, n = 30), whereas Group II received 20 ml of bupivacaine hydrochloride 0.25% + 2 ml saline (Control group, n = 30) for RS block on each side. By providing less morphine consumption, longer duration of analgesia, and lower visual analogue scale score, midazolam addition to bupivacaine for RS blockade was shown to offer adjuvant analgesia.
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