Nalagatla N, et al. - In a retrospective study and meta-analysis, the researchers investigated the short-term or long-term efficacy of accelerated infliximab induction therapy for patients with acute severe ulcerative colitis (ASUC). From 2005 through 2017, data was collected from 213 subjects with steroid refractory ASUC who received infliximab rescue therapy at 3 centers. No association was found between accelerated infliximab induction therapy and lower rates of colectomy in subjects with ASUC, compared to standard induction therapy, however, confounding by disease severity cannot be excluded.