Baggetta R, et al. - Because older adult dialysis patients represent the frailest subgroup of the end-stage renal disease (ESRD) population, researchers investigated whether physical exercise program could mitigate the age-related decline in muscle mass and function in this patient population. They randomized dialysis patients of the EXCITE trial aged > 65 years (active arm, n = 53; control arm, n = 62) to a home-based, low-intensity physical exercise program. Patients were examined at baseline and 6 months after exercise training. The exercise group vs the control group demonstrated improvements in both the 6-minute walking distances and the 5-time Sit-To-Stand time, which was a result of the training program. In this secondary analysis of the EXCITE trial, the investigators found a home-based exercise program improved physical performance and was well tolerated in elderly ESRD patients.