Bahrami N, et al. - Via evaluating MRIs of 33 patients with high-grade gliomas before and after the initiation of bevacizumab, researchers determined if quantifying the sharpness of the fluid-attenuated inversion recovery hyperintense border using a measure derived from texture analysis—edge contrast—improves the evaluation of response to bevacizumab in patients with high-grade gliomas. In patients with high-grade gliomas, texture analysis using edge contrast of the FLAIR hyperintense region seemed to be a significant predictive indicator following treatment with bevacizumab. Specifically, low FLAIR edge contrast may partially suggest areas of early tumor infiltration. This study suggests the significance of quantifying features for determining outcomes in patients with high-grade gliomas.