Jentzer JC, et al. - Whether transthoracic echocardiogram (TTE)-detected systolic or diastolic dysfunction could predict mortality after out-of-hospital cardiac arrest (OHCA), was investigated in this retrospective cohort study of 173 OHCA subjects undergoing targeted temperature management who underwent TTE during hospitalization. The links between TTE measurements of systolic and diastolic function and systemic hemodynamics with all-cause mortality were assessed using univariate analysis and multivariate logistic regression. They found that mortality after OHCA was independently predicted by diastolic dysfunction (higher medial mitral E/e' ratio) on TTE but not by systolic dysfunction and TTE hemodynamic parameters. These data indicated a novel use of Doppler TTE to predict outcomes after OHCA.