Sethi S, Goel N, Ghai B, et al. - Given that the optimum sevoflurane EC₅₀ (End-tidal) needed for CLMA (Classic Laryngeal Mask airway) insertion in unpremedicated children is documented to be in the range of 1.5-2.0%, researchers investigated the feasibility of CLMA insertion at shorter equilibration time points of 2.5 min and 5 min and thus estimated the EC50 of sevoflurane for CLMA insertion at these shorter equilibration times respectively in this randomized trial. This analysis involved children aged 2_8 years of either gender having American Society of Anesthesiologists status I receiving elective cataract surgery. In this study sample, EC₅₀ of sevoflurane for insertion of classic LMA in 100% oxygen was estimated to be 1.1% at 2.5 min and 1.6% at 5.0 min. At 2.5 min and at 5.0 min, the derived EC₉₅ was 1.8% and 1.8%, respectively. Based on these findings, maintaining end-tidal sevoflurane of 1.6% for 2.5 min and 1.8% for 5 min was suggested for successful CLMA insertion.