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Early response to warfarin initiation and the risk of venous thromboembolism after total joint arthroplasty

Journal of the American Academy of Orthopedic Surgeons Feb 16, 2018

Edelstein AI, et al. - This trial was conducted to assess whether, following warfarin initiation in total joint arthroplasty patients, a rapid increase in the international normalized ratio was a risk factor for venous thromboembolism. Experts noted a rapid rise in this ratio to be associated with an increased risk of symptomatic venous thromboembolism. The results identified a population at risk of the symptomatic venous thromboembolism.
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