Looijaard WGPM, et al. - Through a retrospective database study in mechanically ventilated, adult critically ill patients with an abdominal CT-scan fit for skeletal muscle evaluation around ICU admission, admitted from January 2004 to January 2016 (n = 739), experts ascertained the correlation between early protein consumption (day 2–4) and mortality in critically ill ICU individuals with normal skeletal muscle area, low skeletal muscle area, or combined low skeletal muscle area and -density. Individuals were given protocolized nutrition with protein target 1.2–1.5 g/kg/day. In critically ill patients with low skeletal muscle area and -density, early high protein consumption was correlated with lower mortality, though not in individuals with normal skeletal muscle area on admission. These conclusions may be an additional step to personalized nutrition, however, randomized studies are required to assess causality.