Farag S, et al. - The experts undertook this study to examine whether early evaluation of response affects treatment decisions in gastrointestinal stromal tumor (GIST) patients treated with neoadjuvant intent. In GIST patients harboring the non–KIT exon 11 mutation, performing ¹⁸F-FDG PET for early evaluation of response often resulted in a change of management. This ought to be considered the standard of care in GIST patients treated with neoadjuvant intent.