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Early epileptiform discharges and clinical signs predict nonconvulsive status epilepticus on continuous EEG

Neurocritical Care Jul 18, 2018

Koren J, et al. - Researchers evaluated the predictive value of changes within the first 30 minutes of electroencephalography (EEG) as well as of clinical parameters for the occurrence of nonconvulsive status epilepticus (NCSE) during subsequent critical care continuous electroencephalography (CCEEG) using logistic regression and binary classification tests. Findings demonstrated high sensitivity and high negative predictive value of early sporadic epileptiform discharges (SED) and early rhythmic and periodic EEG patterns of “ictal–interictal uncertainty” (RPPIIIU) within the first 30 min of EEG as well as of clinical signs of nonconvulsive seizures in predicting the occurrence of NCSE during subsequent CCEEG. Moreover, these showed potential utility regarding the selection of patients who should undergo CCEEG.

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