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Early diet in preterm infants and later cognition: 10-year follow-up of a randomized controlled trial

Pediatric Research Feb 12, 2021

Embleton ND, Wood CL, Pearce MS, et al. - Since the postdischarge period may be critical to influence growth and cognitive outcomes, researchers conducted this investigation to analyze the impacts of postdischarge nutrition on childhood cognition. Preterm-born children were randomized to either preterm formula (PTF) or term formula (TF) at ~36 weeks corrected age (CGA) up to 6 months, or PTF up to40 weeks CGA, then TF up to 6 months (crossover group). Participants in the study were 92 children (mean 10.1 years). Although there is no long-term effect on childhood cognition of post-discharge macronutrient enrichment, better results are correlated with greater weight and head growth in specific epochs. In order to determine the optimal early diet in preterm infants, further studies are required.

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