Asano S, et al. - Authors quantified 97 eyes of 69 primary open-angle glaucoma subjects to prove the value of the binomial pointwise linear regression (PLR) method to detect the progression of the visual field (VF) in the central 10 degrees in glaucoma cases. They observed that the binomial PLR was equivalent to permutation analysis of PLR (PoPLR) and mean deviation (MD) trend analyses in the positive predictive value (0.19 to 0.80), the negative predictive value (0.86 to 1.0), and the false positive rate (0.0 to 0.13) in the calculation of glaucomatous VF progression. They also noted a shorter time required to detect VF progression (4.2 ± 1.8 years) with the binomial PLR method when compared with PoPLR and MD trend analysis.