Woodle ES, Gill JS, Clark S, et al. - Researchers undertook this prospective multicenter randomized double-blind placebo-controlled trial to compare long-term renal transplant results of patients randomly assigned to continue or withdraw corticosteroids. Participants were low– to moderate–immune risk adult recipients of a living or deceased donor renal transplant without delayed graft function or short-term rejection in the first week post-transplant. Randomization of patients was done to receive tacrolimus and mycophenolate mofetil with or without corticosteroids 7 days post-transplant. A median follow-up of 15.8 years post-transplant revealed that kidney allograft survival did not differ between treatment groups. As inferred based on findings, there may be no necessity of long-term corticosteroids as a component of a calcineurin-based multiple drug immunosuppressive regimen in low– to moderate–immune risk renal transplant recipients.