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Early clinical features of cerebral palsy in children without perinatal risk factors: A scoping review

Pediatric Neurology Aug 16, 2019

Garfinkle J, Li P, Boychuck Z, et al. - By searching six electronic databases, a scoping review was conducted to identify clinical characteristics correlated with the early detection of cerebral palsy (CP) that would be useful for primary care providers. Included studies (n = 41; 27 overview studies and 14 original studies) were categorized by three themes. Early hand preference on clinical history, delayed or absent attainment of motor developmental milestones on developmental screening, and persistent primitive reflexes on neurological examination were the most commonly identified features from each theme. In the specific context of well-baby care surveillance, the literature was scant and lacked consistency regarding early visible clinical signs that should trigger an investigation into possible CP. Further study should concentrate on assessing the value of clinical characteristics for this purpose that are easily recognizable.

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