Early clinical complete blood count changes in severe burn injuries
Burns Oct 04, 2018
Sen S, et al. - Researchers examined the trend in the components of the complete blood count (CBC) in severely burned patients over the first week after injury, and compared survivors and non-survivors regarding differences in CBC components. Upon 5-year retrospective review of adult burn patients with a TBSA?of ≥?15%, they noted decreased HBG and HCT over the first week following injury. Initially, WBC counts were elevated but, over the first 4?days, the counts decrease. Over the first 4?days, a decrease in PLT was noted. Compared with survivors, non-survivors had lower HBG, HCT, RCC, and PLT over the first week but had higher WBC. During the first week, non-survivors had elevated RDW. In non-survivors, MPV was elevated at the end of the first week, and mortality was noted in independent association with MPV on day 7. Non-survivors received more transfusions of blood products compared with survivors during the first week after injury.
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