Pereira MP, et al. - This study inspected the epidemiology, clinical profile, natural course, underlying causes, available treatments and economic burden of itch-related prurigo. The yielded definition and terminology of chronic prurigo (CPG) ought to be implemented in dermatology for harmonizing the communication in the clinical routine, clinical trials and scientific literature. Acute/subacute forms of prurigo displayed as separate entities. These ought to be differentiated from CPG. Its additional analysis would provide relevant clinical data on various aspects of CPG.

Methods

• The basis for a consensus conference were discussions and surveys between members of the TFP.
• The consensus was defined as an agreement ≥75% among the present members, via the Delphi technique.

Results

• 24 members of the TFP took part in the consensus conference.
• Experts consented that CPG be used as an umbrella term for the range of clinical manifestations (e.g. papular, nodular, plaque or umbilicated types).
• CPG was regarded as a distinct disease defined by the presence of chronic pruritus for ≥6 weeks, history and/or signs of repeated scratching and multiple localized/generalized pruriginous skin lesions (whitish or pink papules, nodules and/or plaques).
• The CPG occurrence was the result of a neuronal sensitization to itch and the development of an itch-scratch cycle.