Cindil E, Erbas G, Akkan K, et al. - This imaging study was intended to evaluate the reproducibility and validity of quantitative perfusion parameters derived from dynamic volume perfusion CT in patients with critical limb ischemia (CLI) and to estimate perfusion parameter changes before and after endovascular revascularization. Researchers included 16 individuals with CLI referred for unilateral extremity endovascular arterial recanalization. The study analyzed CT examinations obtained 1–3 days before the procedure and then within 1 week after the treatment at two reading sessions. The estimated blood flow (BF), blood volume (BV), and time to peak (TTP) on color-coded maps and compared statistically. As a reproducible method, it was indicated that dynamic volume perfusion CT of the foot may enable quantitative evaluation of the perfusion of soft tissues and also give a new way of estimating response to endovascular recanalization in CLI.