Dynamic of changes in coronary artery calcification in early rheumatoid arthritis patients over 18 months
Rheumatology International May 16, 2018
Udachkina HV, et al. - Authors evaluated the dynamic of coronary artery calcification (CAC) scores in early rheumatoid arthritis (RA) patients for 18 months. They enrolled 74 RA adult patients (ACR/EULAR criteria, 2010, duration ≤12 months, with moderate/high RA activity, without prior administration of disease-modifying anti-rheumatic drugs or glucocorticoids) within the framework of the observational study: women 73%, median age 56 years, median RA duration 6 months, median DAS28[ESR] 5.4. High incidence of CAC progression was seen in early RA patients older than 45 years during 18 months. Increase in AS which exceeded the median annual progression of Agatston Score in the MESA was seen in more than half of the early RA patients. Experts noted an association of the CAC progression with male gender, AH and lower baseline TC level. No relationship between CAC progression and statin therapy, RA activity and type of anti-rheumatic therapy was noted.
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