Ma SJ, et al. - In order to define the ideal duration of chemotherapy (C) prior to chemoradiation for resected primary stage I-II, cT1-3N0-1M0, and unresected stage III, cT4N0-1M0 pancreatic adenocarcinoma, researchers queried the National Cancer Database (NCDB). Cohorts I-II and III comprised stage I-II and stage III cases, respectively. Stratification of patients was done according to short (short C) and long duration (long C) of chemotherapy based on their median durations. For both resected stage I-II and unresected stage III pancreatic cancer, a survival benefit was achieved with the use of longer duration of chemotherapy vs the shorter duration in this NCDB study using propensity score-matched analysis.