Mamo Y, et al. - Considering the safety and efficacy of fecal microbiota transplant (FMT) for treatment of recurrent Clostridium difficile infection (RCDI), researchers investigated FMT for its durability, long-term clinical outcomes, and patient satisfaction. They performed a follow-up survey of outcomes after FMT at a median of 22 months follow-up and noted that 82% of patients had durable cure of CDI. More post-FMT antibiotic exposure was observed among patients with recurrence, highlighting the necessity for thoughtful antibiotic use and a potential role for prophylactic microbiome enrichment to reduce recurrence.