de Bruin-Weller M, et al. - Authors in Europe assessed how well dupilumab injections improved rashes, itch, and daily lives of people whose atopic dermatitis (AD) required ciclosporin, but for whom ciclosporin wasn't working or caused intolerable side effects, or whose medical conditions prevented its use. As per data, itch, other symptoms, mood, and quality of life were also improved with dupilumab. Among dupilumab-treated patients, conjunctivitis and injection-site reactions were more frequent; with placebo, skin infections (excluding herpes) and AD exacerbations (worsening) were more frequent. AD was significantly improved with dupilumab plus topical corticosteroids even in adults with AD who had previously failed treatment with or were unable to use ciclosporin.