Lenga L, et al. - In patients with hypoattenuating liver metastases from colorectal cancer (CRC) at abdominal dual-energy CT (DECT), researchers evaluated the value of the noise-optimized virtual monoenergetic imaging (VMI+) technique on quantitative and qualitative image parameters. In this IRB-approved study, 53 consecutive subjects with histologically proven, hypoattenuating liver metastases from CRC were retrospectively involved. In comparison with standard reconstructions and traditional VMI series at abdominal DECT, low-keV VMI + reconstructions showed significantly increased quantitative and qualitative image quality parameters in patients with hypoattenuating liver metastases from CRC. The study findings suggested that best lesion delineation could be achieved at 40-keV VMI+.