Volterrani L, Gentili F, Fausto A, et al. - Researchers intended to evaluate the feasibility of dual-energy CT (DECT) for locoregional staging of breast cancer and differentiation of tumor histotypes. This study included a sum of 31 individuals (mean [± SD] age, 55.8 ± 14.8 years) with breast cancer diagnosed by needle biopsy who underwent preoperative contrast-enhanced DECT for staging purposes from a retrospective review of institutional databases between January 2016 and July 2017. They noted attenuation values and iodine concentration of tumors and normal breast tissue and the ratios of these findings in each tissue type. Cancers were categorized as ductal carcinoma in situ, invasive ductal carcinoma, and invasive lobular carcinoma. At histopathologic analysis, a total of 64 tumor lesions were found vs 67 on DECT for 34 breasts (three bilateral cancers were included). The dual-energy CT was found to be feasible and appears to be a reliable tool for the locoregional staging of breast cancer.