Schneider R, et al. - Herein, researchers ascertained if exosomal microRNAs (miRNAs) in cerebrospinal fluid (CSF) of patients with frontotemporal dementia (FTD) presented as diagnostic biomarkers by evaluating the miRNA expression in the Genetic Frontotemporal Dementia Initiative (GENFI) cohort and in sporadic FTD. Findings demonstrated that only miR-632 was substantially decreased in sporadic FTD than Alzheimer’s disease (AD) and healthy controls (HCs). Hence, it was deduced that exosomal miR-204-5p and miR-632 encompassed the potential as diagnostic biomarkers for genetic FTD and miR-632, also for sporadic FTD.