Ng WT, Lee MCH, Fung NTC, et al. - In this exploratory study involving 91 patients, researchers sought to investigate the dose-volume impacts of re-irradiation for locally recurrent nasopharyngeal carcinoma and endeavors to discover the optimal dose for the best survival. The local control, fatal complication, and overall survival have been examined against the dose (in Equivalent Dose at 2 Gy/fractions) and recurrent gross tumor volume (GTV). According to results, the local control and fatal complication rate seem to increase with the prescribed dose. Findings revealed that GTV volume plays an important part in local control. A 60 Gy₁₀ seems to be optimal for the best survival result. For small tumors, higher doses could be considered. There was no association between the fatal complication rate and GTV volume.