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Dosage of exogenous gonadotropins is not associated with blastocyst aneuploidy or live-birth rates in PGS cycles in Chinese women

Human Reproduction Sep 22, 2018

Wu Q, et al. - Researchers investigated whether the total dose of exogenous gonadotropins is related to blastocyst aneuploidy or live-birth rates in preimplantation genetic screening cycles in Chinese women (n=944). They found that, after adjusting for confounding factors, the dose of exogenous gonadotropins was not associated with the blastocyst aneuploidy rate. Additional findings showed that the live-birth rates after single cryopreserved blastocyst transfers were also not significantly associated with the gonadotropins dose. These results suggested that the high doses of gonadotropins used in ART cycles may be safe.

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