Kim YH, et al. - This study was performed on patients undergoing primary bilateral total knee arthroplasties (TKAs) without use of chemical thromboprophylaxis, with an intent to determine if tranexamic acid reduces the blood loss and transfusion rate and volumes; increase the prevalence of deep vein thrombosis (DVT). Furthermore, factors associated with DVT were also investigated. In Asian patients who underwent primary bilateral simultaneous sequential TKAs and did not receive routine chemical thromboprophylaxis after the operation, reduction in the volume of blood transfusion, without any increase in the prevalence of DVT or PE, was evident consequent to tranexamic acid use.