Wu Y, Wu X, Pan H, et al. - As the impact of emergency department length of stay (EDLOS) on outcomes of patients with acute ischemic stroke (AIS) remains largely unexamined, researchers intended to determine if there is a connection between EDLOS and outcomes in patients with AIS. Six hundred eighteen AIS patients were recruited. Baseline demographics, vascular risk factors, ED admission information, hyperacute treatment of AIS, and stroke severity have been obtained. Data reported that the median EDLOS was 2.5 h (1.4–6.9 h). On multivariable linear regression, the month of presentation between April and June, admission at the ED between 7 a.m. to 3 p.m., transferring to the stroke unit, receiving endovascular interventional treatment, onset on holidays, and progressive stroke were correlated with shorter EDLOS.  Short EDLOS was related to increased risk of stroke progression in AIS patients, possibly reflecting prioritized admission of more severely affected patients at high risk of stroke progression. EDLOS alone may be a weak predictor of stroke care in the ED.