Chung SJ, et al. - The effects of levodopa sparing on the development of levodopa-induced dyskinesia were investigated in Parkinson’s disease. For this study, medical records for patients with de novo Parkinson’s disease who visited the Yonsei Parkinson Center between April 2009 and June 2015 and received at least 2 years of treatment were retrospectively reviewed. Findings revealed a minimal risk of dyskinesia in association with late levodopa administration after adjusting for confounding effects. In Parkinson’s disease, this could be a reasonable strategy for prolonging the levodopa-induced dyskinesia-free period.