Does intensity-modulated radiation therapy lower the risk of osteoradionecrosis of the jaw? A long-term comparative analysis
International Journal of Oral & Maxillofacial Surgery Jun 27, 2019
Willaert R, et al. - Via evaluating medical files and radiological images of 109 patients treated with primary intensity-modulated radiation therapy (IMRT) and 129 patients treated with primary three-dimensional conformal radiotherapy, researchers examined the effect of different radiation techniques on the long-term incidence of osteoradionecrosis in head and neck cancer. In a retrospective, comparative, observational study, risk factors and the occurrence of osteoradionecrosis were analyzed. During a mean follow-up of 4.3 years, 22 patients developed osteoradionecrosis. Multivariate analysis exhibited evidence of a higher risk of osteoradionecrosis in patients with an oropharynx tumour and after radiation therapy in patients with a tooth extraction. Although the incidence of osteoradionecrosis tended to be lower after IMRT, it remains a serious problem due to multifactorial aetiology and cannot be prevented by new techniques of radiotherapy. In order to control additional risk factors and prevent osteoradionecrosis, continuous attempts are required.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
-
Exclusive Write-ups & Webinars by KOLs
-
Daily Quiz by specialty
-
Paid Market Research Surveys
-
Case discussions, News & Journals' summaries